Molecular Details
DICL_CP_0307283
- (2R)-2-amino-3-hydroxypropanoic acid
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0307283
PubChem CID
Molecular Formula
C3H7NO3 Molecular Weight
105.093 g/mol
Synonyms/Alias
[D-serine; 312-84-5; H-D-Ser-OH; (R)-2-amino-3-hydroxypropanoic acid; (R)-Serine; Serine D-form; (2R)-2-amino-3-hydroxypropanoic acid; Serine; D-; D-Serin; MFCD00004269; C3H7NO3; (2R)-2-amino-3-hydrox...
InChI Key
MTCFGRXMJLQNBG-UWTATZPHSA-N
InChI
InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
IUPAC Name
(2R)-2-amino-3-hydroxypropanoic acid
CAS Number
2768959-22-2
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
14 13 0 0 0 0 0 0 0 0999 V2000
-1.1680 0.3976 0.5953 C 0 0 0 0 0 0 0 0 0 0 0 0
-0.1182 -0.5954 0.0704 C 0 0 2 0 0 0 0 0 0 0 0 0
1.2506 -0.218...
Experimental Data
Activity Data
Target Ion Channel
Glutamate receptor ionotropic subunit NMDA 1/2A
Uniprot Accession Number
Function
Agonist
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
EC50: 1000 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
−40 mV mV
Temperature
Room Temperature
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte
Binding Information
Binding Site
Extracellular domain
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
7
Rotatable Bonds
2
logP
-1.6094
Complexity
22.697
TPSA (Ų)
83.55
H-Bond Donors
3
H-Bond Acceptors
3
Ring Count
0